We use a Content Compliance Rule that quarantines any email that comes in from specific top level domains that are typically used for malicious activity. This can be but isn't limited to country top level domains. Create a rule, Inbound, If any of the following match the message, add a setting, advanced content match, location Full headers, matches regex, use the regex below as your template, save and then decide how you want to handle those messages. You can add as many regex expressions as you need.
[\w.+\-]{0,50}\.xyz(\W|$)
The .xyz is the top level domain you want to block. Just replace that with the domain you want to control.
Hope this helps give you another option.